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Models

About 42,530 results
마우스

hTHPO

모델명：C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000062

The endogenous mouse Thpo gene was replaced by human THPO gene.

마우스

hCD73(2)

모델명：C57BL/6Smoc-Nt5etm3(NT5E)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200009

The endogenous mouse Nt5e gene was replaced by human NT5E gene.

마우스

hPSGL-1

모델명：C57BL/6Smoc-Selplgem1(hSELPLG)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-00046

The endogenous mouse Selplg gene was replaced by human SELPLG gene.

마우스

hLAG3/hCTLA-4

모델명：B6.129S-Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-190018

This LAG3 and CTLA4 double knockin strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

마우스

hCD93

모델명：C57BL/6Smoc-Cd93em1(hCD93)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-215065

The endogenous mouse Cd93 gene was replaced by human CD93 gene.

마우스

Fah-KO(NMG)

모델명：NOD-PrkdcscidIl2rgem1Fahem2Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-NSG-004

Exon 3 of Fah gene was deleted to generate Fah knockout mice.

마우스

hCXCR3

모델명：C57BL/6Smoc-Cxcr3em1(hCXCR3)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-200219

The endogenous mouse Cxcr3 gene was completely or partially replaced by human CXCR3 gene via ESC targeting.

마우스

Trpv1-IRES-Cre

모델명：C57BL/6Smoc-Trpv1em1(Myc-IRES-Cre)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200139

A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.

마우스

hHER3(2)

모델명：C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-225068

The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.

마우스

Avp-IRES-Cre

모델명：C57BL/6Smoc-Avpem1(IRES2-Cre-WPRE-polyA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200142

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

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