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Models

About 42,530 results
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hSIRPA(2)/hCD47

모델명:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
모델 상태:Repository Live | 카탈로그:NM-HU-2000111

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

마우스

C9orf72-KO

모델명:C57BL/6Smoc-C9orf72em1Smoc
모델 상태:Sperm cryopreservation | 카탈로그:NM-KO-201246

Exon 4-5 of C9orf72 gene was deleted to generate C9orf72 knockout mice.

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hPD-1(BALB/c)

모델명:BALB/cAnSmoc-Pdcd1em1(hPDCD1)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-190079

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

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Avpr1a-KO

모델명:C57BL/6Smoc-Avpr1aem1Smoc
모델 상태:Sperm cryopreservation | 카탈로그:NM-KO-200043

Exon 1-2 of Avpr1a gene was deleted to generate Avpr1a knockout mice.

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BALB/c Nude

모델명:BALB/cAnSmoc-Foxn1nu/Smoc
모델 상태:Repository Live | 카탈로그:SM-014

This strain carries a Foxn1nu mutation on the BALB/c background which will lead to T cell deletion. At the same time, the response to thymus-dependent antigens is limited, resulting in impaired B cell function while NK cells, macrophages, and antigen-presenting cells function normally. The complement activity is normal as well. Hair dysplasia causes aberrant hair growth in which the majority of the hair cannot protrude from the surface, resulting in a naked mouse phenotype.

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Angptl6-KO

모델명:C57BL/6Smoc-Angptl6em1Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-KO-201240

Exon 3 of Angptl6 gene was deleted to generate Angptl6 knockout mice.

마우스

hIDO1

모델명:B6;129S-Ido1tm1(hIDO1)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-00061

The endogenous mouse Ido1 gene was replaced by human IDO1 gene.

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Aldh5a1-KO

모델명:C57BL/6Smoc-Aldh5a1em1Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-KO-201238

Exon 3-7 of Aldh5a1 gene was deleted to generate Aldh5a1 knockout mice.

마우스

hPD-1/hSEMA4D

모델명:C57BL/6Smoc-Pdcd1em1(hPDCD1)Sema4dem1(hSemA4D)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-190033

hPD-1(NM-HU-00015) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-1/hSEMA4D.

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hIL11RA

모델명:C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-HU-204982

The endogenous mice Il11ra1 gene was replaced by human IL11RA gene.

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