모델명:C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
모델 상태:Repository Live | 카탈로그:NM-KI-200123
A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site.
Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.