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Models

About 42,530 results
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Abcb8-Flox

모델명：C57BL/6Smoc-Abcb8em1(flox)Smoc
모델 상태：Developing | 카탈로그：TBD

These mice carry loxP sites flanking target exons of Abcb8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb8 gene.

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hIL2

모델명：C57BL/6Smoc-Il2tm3(hIL2)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-190048

The endogenous mouse Il2 gene was replaced by human IL2 gene.

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R26-CreERT2

모델명：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200041

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.

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hSERPINC1

모델명：C57BL/6Smoc-Serpinc1tm1(hSERPINC1)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-225075

The endogenous mouse Serpinc1 gene was replaced by human SERPINC1 gene.

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MHC Class II(I-A/I-E)-KO(Nod-Scid)

모델명：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
모델 상태：Developing | 카탈로그：NM-KO-18057

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.

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hPD-L1/hSIGLEC15

모델명：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

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Foxp3-IRES-Luc-2A-tdTomato

모델명：C57BL/6Smoc-Foxp3em1(IRES-Luci-2A-tdTomato)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200065

A IRES-luci-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

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H11-CAG-RSR-tdTomato

모델명：C57BL/6Smoc-Igs2em1(CAG-RSR-tdTomato)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-18009

These mice harbor a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette in mouse H11 locus via homologous recombination.

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R26-Renilla-Luc

모델명：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-Renilla-Luc)-NSmoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00091

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Renilla-Luc gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

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Nphs2-CreERT2

모델명：C57BL/6Smoc-Nphs2tm1(IRES-CreERT2)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-00128

An IRES-CreERT2 co-expression cassette is inserted into 3'UTR region of Nphs2 gene via homologous recombination to establish a tamoxifen inducible Nphs2-CreERT2 tool stain.

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