肠炎模型


化疗性肠炎小鼠模型

原理  小鼠腹腔注射一定剂量5-FU诱导小鼠出现化疗损伤性肠炎,模拟人类接受化疗后出现的状况。

样本要求  常规实验小鼠

服务周期  10个工作日

技术指标  1)客户可自行选择性别,雄性小鼠症状较雌性严重;2)检测服务包括DAI(疾病指数)评价及病理检测等。


炎性肠炎小鼠模型

原理  通过给予小鼠饮用不同剂量的DSS(硫酸葡聚糖钠)溶液,诱导小鼠出现急性/慢性肠炎。机制:可能因DSS导致肠屏障损坏,巨噬细胞功能失调、菌群失调等多因素导致,也可能与Th1、Th2细胞的调控有关。

样本要求  常规实验小鼠 8周龄

服务周期  急性肠炎9个工作日,慢性肠炎21个工作日

技术指标  1)客户可自行选择性别,雄性小鼠症状较雌性严重;2)检测服务包括DAI(疾病指数)评价及病理检测等。



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