Lep-KO
모델명
B6;129S-Leptm1Smoc
카탈로그
NM-KO-00034
모델 상태
Repository Live
유전자 요약
Gene Symbol
Lep
모델 설명
검증 데이터
Fig1. Body weight and Blood glucose monitoring of ob/ob mice.
Fig2. Evaluation of Oral glucose tolerance test (OGTT) of female ob/ob mice.
Abbr. HO, homozygous; WT, wild type. **, P ≤ 0.01.
Note. The tested ob/ob and C57BL/6 mice were 6 weeks old.
Fig3. Detection of insulin levels in serum by ELISA.
Abbr. Hom, homozygous; HE, heterozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old.
Fig4. H&E staining of the subcutaneous adipose tissue (SAT) in ob/ob mice.
Abbr. HO, homozygous; WT, wild type; WAT, white adipose tissue; BAT, brown adipose tissue.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 20.
Fig5. Representative pictures of pancreas in ob/ob mice.
These results suggested the inflammatory cell infiltration of the pancreas in ob/ob mice.
Abbr. HO, homozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 10.
당신은 또한 좋아할 수 있습니다
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
조회Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
조회