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Models

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Aadacl2fm2-Flox

모델명:C57BL/6Smoc-Aadacl2fm2em1(flox)Smoc
모델 상태:Developing | 카탈로그:TBD

These mice carry loxP sites flanking target exons of Aadacl2fm2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl2fm2 gene.

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Mertk-KO

모델명:C57BL/6Smoc-Mertkem1Smoc
모델 상태:Repository Live | 카탈로그:NM-KO-200362

Exon 2 of Mertk gene was deleted to generate Mertk knockout mice.

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hAPP

모델명:C57BL/6Smoc-Apptm(hAPP)Smoc
모델 상태:Sperm cryopreservation | 카탈로그:NM-KI-220224

The endogenous mouse APP gene was replaced by human APP gene.

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Pd-1-KO

모델명:C57BL/6Smoc-Pdcd1em3Smoc
모델 상태:Repository Live | 카탈로그:NM-KO-190423

The Pdcd1 knockout mouse model was generated by knocking out the exon2-4 region of the Pdcd1.

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Nmu-2A-Cre

모델명:C57BL/6Smoc-Nmuem1(2A-Cre-WPRE-polyA)Smoc
모델 상태:Repository Live | 카탈로그:NM-KI-200298

2A-Cre-WPRE-polyA expression cassette was knocked into the Nmu gene stop codon site. Nmu gene encodes a member of the neuromedin family of neuropeptides. The encoded protein plays a role in energy homeostasis and body temperature regulation. And the protein is homologous with human NMU, which is linked toobesity.

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Atrn-2A-Cre

모델명:C57BL/6Smoc-Atrnem(2A-Cre)Smoc
모델 상태:Sperm cryopreservation | 카탈로그:NM-KI-215077

2A-Cre expression cassette was knocked into the Atrn gene .

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R26-CAG-LSL-hEZH2*Y646N-IRES-Luc-2A-tdTomato

모델명:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato)Smoc
모델 상태:Embryo cryopreservation | 카탈로그:NM-KI-190073

These mice harbor a CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

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Aagab-KO

모델명:C57BL/6Smoc-Aagabem1Smoc
모델 상태:Developing | 카탈로그:TBD

Exon 2 of Aagab gene was deleted to generate Aagab knockout mice.

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Tagln-2A-DreERT2

모델명:C57BL/6Smoc-Taglnem1(2A-DreERT2)Smoc
모델 상태:Sperm cryopreservation | 카탈로그:NM-KI-215038

2A-DreERT2 expression cassette was knocked into the Tagln gene. Tagln-2A-DreERT2(2) (Stock No.NM-KI-215094) is similar to this strain.

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Dmp1-2A-CreERT2

모델명:C57BL/6Smoc-Dmp1em(2A-CreERT2)1Smoc
모델 상태:Sperm cryopreservation | 카탈로그:NM-KI-225004

2A-CreERT2 expression cassette was knocked into the Dmp1 gene .

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