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Models

About 42,530 results
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Notch1-CreERT2

모델명：C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200122

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

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Hcn4-DreERT2

모델명：C57BL/6Smoc-Hcn4em1(kozak-DreER-WPRE-A)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-200199

A kozak-DreER-WPRE-pA expression cassette was knocked into the Hcn4 gene start codon site.

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Abcc8-KO(2)

모델명：C57BL/6Smoc-Abcc8em2Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KO-225150

exon 8-16 of Abcc8 gene was deleted to generate Abcc8 knockout mice.

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hMAPT

모델명：C57BL/6Smoc-Mapttm1(hMAPT)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-200116

The endogenous mouse Mapt gene was replaced by human MAPT gene. While hMAPT(2)(Stock No.NM-HU-200257) mice function similarly to hMAPT mice,for more detailed information please contact our technical advisor.

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Taar1-KO

모델명：C57BL/6Smoc-Taar1em1Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KO-2112327

Exon 1 of Taar1 gene was deleted to generate Taar1 knockout mice.

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Mcpt8-2A-CreERT2

모델명：C57BL/6Smoc-Mcpt8em1(2A-CreERT2-WPRE-polyA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200006

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Mcpt8 gene stop codon site.

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Myf6-CreERT2

모델명：C57BL/6Smoc-Myf6em1(CreERT2-pA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-200125

A CreERT2-pA expression cassette was knocked into the Myf6 gene start codon site. Myf6 (myogenic factor 6) is a DNA-binding protein involved in muscle development. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Myf6.

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Ywhaz-KO

모델명：C57BL/6Smoc-Ywhazem1Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KO-202154

Exon 4 of Ywhaz gene was deleted to generate Ywhaz knockout mice.

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Ctnnb1-Flox

모델명：C57BL/6Smoc-Ctnnb1em1(flox)Smoc
모델 상태：Repository Live | 카탈로그：NM-CKO-200154

These mice carry loxP sites flanking exon 2-6 of Ctnnb1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ctnnb1 gene.

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Aa465934-KO

모델명：C57BL/6Smoc-Aa465934em1Smoc
모델 상태：Developing | 카탈로그：TBD

Exon 1-3 of Aa465934 gene was deleted to generate Aa465934 knockout mice.

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