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Models

About 42,530 results
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Sidt2-Flox

모델명：B6;129S-Sidt2tm1(flox)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-CKO-00041

The Sidt2 flox allele has loxP sites flanking exon 2 of Sidt2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

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Foxn1-IRES-Cre

모델명：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

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hPD-L1(BALB/c)

모델명：BALB/cAnSmoc-Cd274em(hPD-L1)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-220028

The hPD-L1(NM-HU-00062) mice were backcrossed to BALB/c genetic background, to create the new strain of hPD-L1(BALB/c) (NM-HU-220028) mice.

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hMARCO

모델명：C57BL/6Smoc-Marcoem1(hMARCO)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000029

The endogenous mouse Marco gene was replaced by human MARCO gene.

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Zfp36-KO

모델명：C57BL/6Smoc-Zfp36em1Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-2112247

exon 2 of Zfp36 gene was deleted to generate Zfp36 knockout mice.

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Il34-Luc-2A-EGFP

모델명：B6;129S-Il34tm1(Luc-eGFP)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-00035

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il34.

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Gad1-2A-eGFP

모델명：C57BL/6Smoc-Gad1em(2A-eGFP)Smoc
모델 상태：Developing | 카탈로그：NM-KI-220179

2A-eGFP expression cassette was knocked into the Gad1 gene stop codon site.

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Ucp1-Cre

모델명：C57BL/6Smoc-Ucp1em2(Kozak-Cre-WPRE-pA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190105

A Kozak-Cre-WPRE-pA expression cassette was knocked into the Ucp1 gene start codon site.

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Avil-Cre

모델명：C57BL/6Smoc-Avilem1(Cre)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-215036

Cre expression cassette was knocked into the Avil gene.

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Myf5-Cre

모델명：C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200147

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

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