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Models

About 42,530 results
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R26-SA-BirA

모델명：B6;129S-Gt(ROSA)26Sortm1(SA-BirA-V5)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00085

A SA-BirA-polyA expression cassette was knocked in mouse Rosa26 loci . Heterozygous knockin mice developed normally.

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hIL2RG

모델명：C57BL/6Smoc-Il2rgem1(IL2RG)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200007

The endogenous mouse Il2rg gene was replaced by human IL2RG gene.

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Wnt1-Dre

모델명：C57BL/6Smoc-Wnt1em1(Dre-Wpre-polyA)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200176

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

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Tie1-2A-Cre

모델명：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-18023

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

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hHGF(NMG)

모델명：NOD-PrkdcscidIl2rgem1Hgfem1(hHGF)Smoc
모델 상태：Developing | 카탈로그：NM-NSG-013

The endogenous mouse Hgf gene was replaced by human HGF gene. (NMG Background)

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hIL2RA/hIL2RB/hIL2RG

모델명：C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210414

hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.

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hCD3EDG(BALB/c)

모델명：BALB/c-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-220122

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

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A2ml1-Flox

모델명：C57BL/6Smoc-A2ml1em1(flox)Smoc
모델 상태：Developing | 카탈로그：TBD

These mice carry loxP sites flanking target exons of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

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hPSGL-1(2)

모델명：C57BL/6Smoc-Selplgem2(hSELPLG)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210026

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

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Cd68-IRES-Cre

모델명：C57BL/6Smoc-Cd68em1(IRES-Cre)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200161

A IRES-Cre expression cassette was knocked into the Cd68 gene stop codon site.

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