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Models

About 42,530 results
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hPVRL2

모델명：C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-2000084

The endogenous mouse Nectin2 gene was replaced by human PVRL2 gene.

마우스

Hopx-2A-DreERT2

모델명：C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-190035

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

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hTP53(2)

모델명：C57BL/6Smoc-Trp53tm1(hTP53)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-225052

The endogenous mouse Trp53 gene was replaced by human TP53 gene.

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Lyz2-2A-CreERT2

모델명：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-18018

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

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hTIGIT(3)

모델명：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-200244

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

마우스

Col1a1-TRE3G-dCas9-VPR-EGFP

모델명：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

마우스

Isl1-CreERT2

모델명：C57BL/6Smoc-Isl1em1(CreERT2) Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KI-00013

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

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Axin2-CreERT2

모델명：C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
모델 상태：Developing | 카탈로그：NM-KI-200109

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

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hSIGLEC15

모델명：C57BL/6Smoc-Siglec15em1(hSIGLEC15)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-190037

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene.

마우스

hTNFR2/hFCGR2B

모델명：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Fcgr2bem3(FCGR2B)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210404

hTNFRSF1B (NM-HU-190010) was crossed with hFCGR2B (NM-HU-2000010) to generate hTNFRSF1B/hFCGR2B mice.

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