R26-CAG-Luc-2A-tdTomato(NMG)

모델명

NOD.Cg-PrkdcscidIl2rgem1Gt(ROSA)26Sorem1(CAG-Luciferase-2A-tdTomato-WPRE-pA)Smoc

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NM-KI-233090

모델 상태

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유전자 요약

Gene Symbol
Gt(ROSA)26Sor

모델 설명

The CAG-Luciferase-2A-tdTomato-WPRE-pA expression cassette was knocked into the R26 locus.

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Fig.1 Detection of tdTomato expression in blood by FACS. 

The result showed that most of all CD45+ cells in R26-CAG-Luc-2A-tdTomato(NMG) mice blood are tdTomato+ cells. (female, WT: 8.6wks, HE: 9.6wks)

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Fig.2 Detection of tdTomato fluorescence by IVIS imaging system. (female, WT: 8.6wks, HE: 9.6wks) 

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Fig.3 Detection of tdTomato expression in multiple tissues. 

The results showed that tdTomato expressed in a variety of tissues in heterozygous R26-CAG-Luc-2A-tdTomato(NMG) mice, including the pancreas, mammary gland, lung, liver, kidney, large intestine, muscle and skin.


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