hGCGR
모델명
C57BL/6JSmo-Gcgrtm(hGCGR)Smoc
카탈로그
NM-HU-215004
모델 상태
Repository Live
유전자 요약
Gene Symbol
Cxcr5
모델 설명
검증 데이터
Fig.1 Detection of Mouse Gcgr expression in liver, kidney, heart, lung, pancreas, brown adipose tissue, white adipose tissue, jejumum, ileum, colon,cortex, cerebellum, hypothalamus and brain stem by RT-PCR.
Wild type: only one band at 226 bp with primers F1/R1(mGcgr);
Homozygous: only one band at 190 bp with primers F2/R2(hGCGR).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of GCGR expression in liver, kidney, heart, lung, pancreas, brown adipose tissue, white adipose tissue, jejumum, ileum, colon,cortex, cerebellum, hypothalamus and brain stem by RT-PCR.
Wild type: only one band at 226 bp with primers F1/R1(mGcgr);
Homozygous: only one band at 190 bp with primers F2/R2(hGCGR).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.3 Detection of hGCGR expression in hGCGR mice by WB.
Abbr. M,marker; HO, homozygous; WT, wild type; PC, positive control, Hela cells.
Note.The anti-GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.
Fig.4 Detection of hGCGR expression in Kidney in hGCGR KI mice.
Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.
Fig.5 Detection of hGCGR expression in Liver in hGCGR KI mice.
Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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