hGCGR

모델명

C57BL/6Smoc-Gcgrem(hGCGR)Smoc

카탈로그

NM-HU-215004

모델 상태

Repository Live

PDF 받기

유전자 요약

Gene Symbol
Cxcr5

Synonyms

Blr1; Gpcr6; MDR15; CXC-R5; CXCR-5

Chromosome

9

NCBI ID

12145

MGI ID

103567

Ensembl ID

ENSMUSG00000047880

Pubmed

Cxcr5

Human Ortholog

CXCR5

모델 설명

The endogenous mice Gcgr gene was replaced by human GCGR gene.

검증 데이터

image.png

Fig1. Detection of GCGR expression in liver by RT-PCR. 

Wild type: only one band at 589 bp with primers F1/R1(mGcgr);

Homozygous: only one band at 501 bp with primers F2/R2(hGCGR).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png


Fig2. Detection of hGCGR expression in hGCGR Mice by WB. 

Abbr. M,marker; HO, homozygous; WT, wild type.

Note. The anti-human GCGR Antibody cross-reacted with mouse GCGR and humanized GCGR.

image.png

Fig3. Detection of hGCGR expression in Kidney in hGCGR KI mice

Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.

image.png

Fig4. Detection of hGCGR expression in Liver in hGCGR KI mice.

Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.



당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회