hF12
모델명
C57BL/6JSmo-F12tm1(hF12)Smoc
카탈로그
NM-HU-210017
모델 상태
Repository Live
유전자 요약
Gene Symbol
F12
모델 설명
검증 데이터
Fig1. Detection of F12 expression in liver by RT-PCR.
Wild type: only one band at 318 bp with primers F1/R1(mF12);
Homozygous: only one band at 274 bp with primers F2/R2(hF12);
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig.2 Detection of human F12 (A) and mouse F12 (B) expression in serum by ELISA (male, 8-11wks, n=2).
Abbr. HO, homozygous; WT, wild type.
Fig.3 Detection of hF12 expression in serum by ELISA (male, n=3).
Abbr. HO, homozygous; WT, wild type.
Fig.4 Detecion of coagulation time in female hF12 knockin mice by APTT (female，n=5, Mean ± SEM, t-test).
Abbr. HO, homozygous; WT, wild type.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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