hHLA-DPA1*03: 01
모델명
C57BL/6JSmo-H2-Aatm1(hHLA-DPA1*03: 01)Smoc
카탈로그
NM-HU-210009
모델 상태
Embryo cryopreservation
유전자 요약
Gene Symbol
H2-Aa
모델 설명
검증 데이터
Fig.1 Detection of HLA-DPA1 expression in large Intestine by RT-PCR. Wild type: one band at 429 bp with primers F1/R1 (mHla-dpa1); Homozygous: one band at 256 bp with primers F2/R2 (hHLA-DPA1). Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig2. Expression characterization of hHLA-DP on human PBMC.
Fig3. Expression characterization of HLA-DPA1*03:01 on DCs in Blood in HLA-DPA1*03:01 KI mice. Note: The anti-hMHC II antibody has been reported to react with a shared epitope of HLA-DR, HLA-DP, and HLA-DQ. The anti-mMHC II antibody reacts with a polymorphic determinant shared by the I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek MHC class II alloantigens from mice carrying H-2p,r,q,b,d,u haplotypes.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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