hICOSL(2)

모델명

C57BL/6Smoc-Icosltm3(hICOSLG)/Smoc

카탈로그

NM-HU-2000068

모델 상태

Embryo cryopreservation

PDF 받기

유전자 요약

Gene Symbol
Icosl

Synonyms

B7h， GI50， GL50， B7-H2， LICOS， B7RP-1， GL50-B， ICOS-L， Icoslg， Ly115l， AU044799， BG071784， mKIAA0653

NCBI ID

50723

MGI ID

1354701

Ensembl ID

ENSMUSG00000000732

Pubmed

Icosl

Human Ortholog

ICOSLG

모델 설명

The endogenous mouse Icosl gene was replaced by human ICOSLG gene. While hICOSL(Stock No.NM-HU-00095) mice function similarly to hICOSL(2) mice,for more detailed information please contact our technical advisor.
신청분야：Immunotherapy,drug screening

검증 데이터

NM-HU-2000068 hICOSLG.png

Fig1. Analysis of ICOSLG gene expression in the spleen by RT-PCR.

Mouse Icoslg mRNA was detectable by P1/2(276bp), human ICOSLG mRNA was detectable by P1/3(406bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human ICOSLG and mouse Icoslg in the spleen.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회