hIL7

모델명

C57BL/6Smoc-Il7tm1(hIL7)Smoc

카탈로그

NM-HU-190031

모델 상태

Embryo cryopreservation

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유전자 요약

Gene Symbol
Il7

모델 설명

The endogenous mouse Il7 gene was replaced by human IL7 gene.

신청분야:Immunotherapy,cancer research,drug screening

검증 데이터

Il17-2.png

Fig.1 mRNA expression identification results of RT-PCR.

P1/2 is specific for mouse-derived sequences, and P3/4 is specific for human-derived sequences.

Heterozygous (HE) and wild-type (WT) mice can amplify a 332bp product with the P1/2 primer pair.

Heterozygous mice can amplify a 386bp product with the P3/4 primer pair, while wild-type mice show no bands.


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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