hIL7
모델명
C57BL/6JSmo-Il7tm1(hIL7)Smoc
카탈로그
NM-HU-190031
모델 상태
Repository Live
유전자 요약
Gene Symbol
Il7
모델 설명
검증 데이터
Fig.1 Detection of IL7 expression in thymus by RT-PCR.
Wild type: only one band at 177 bp with primers F1/R1(mIl7);
Homozygous: only one band at 340 bp with primers F2/R2(hIL7).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of IL7 expression in thymus homogenate by ELISA.
Wild-type C57BL/6 mice (WT, female, 11 weeks old, n=3) and homozygous hIL7 knockin mice (HO, male, 9 weeks old, n=3) were administered poly(I:C) (100 μg/mouse) via intraperitoneal (i.p.) injection. After 6 hours, thymus homogenates were collected for IL7 measurement by ELISA. Human IL7 was detectable in the HO mice. Notably, the ELISA kit used exhibits cross-reactivity between human and mouse IL7 proteins.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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