B2m-KO(NMG)

모델명

NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc

카탈로그

NM-NSG-002

모델 상태

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유전자 요약

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B2m

모델 설명

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

신청분야:immunodeficiency,immune system,transplantation research

검증 데이터

image.png

Fig1. Detection of B2m expression in cerebellum by RT-PCR. 

Wild type: only one band at 139 bp with primers F1/R1(mB2m);


Abbr. M, DNA marker; HO, homozygous;  WT, wild type.

image.png

Fig2. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(M-NSG) mice.


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