B2m-KO

모델명

C57BL/6JSmo-B2mem3Smoc

카탈로그

NM-KO-18021

모델 상태

Repository Live

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유전자 요약

Gene Symbol
B2M

모델 설명

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.
신청분야:immune system

검증 데이터

b2m流式.png

Fig1 . There are few CD8+ cytotoxic T-cells and increase in CD4+ T-cells in B2M knockout mice. Immune responses involving CD8+T-cells are severely deficient providing a model to assess the role of CD8+ cells and class I MHC in various experimental systems. 


간행물 1piece

1. Disruption of palladin results in neural tube closure defects in mice
Published year:2005-08-01 References:Mol Cell Neurosci

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