hTNFR2(BALB/c)
모델명
BALB/cJSmo-Tnfrsf1btm(hTNFRSF1B)Smoc
카탈로그
NM-HU-220499
모델 상태
Embryo cryopreservation
유전자 요약
Gene Symbol
TNFRSF1B
모델 설명
검증 데이터
Fig.1 Expression analysis of hTNFR2 on Treg cells in spleen of hTNFR2(BALB/c) humanized mice.
Leukocytes were collected from spleen of wild-type BALB/c mice (female, 8 weeks) and homozygous hTNFR2(BALB/c) mice (male, 14 weeks) stimulated in vivo with anti-CD3ε and analyzed by flow cytometry with anti-mTNFR2 and anti-hTNFR2. hTNFR2 were exclusively detectable in hTNFR2 humanized mice but not in wild-type mice.
Fig.2 Expression analysis of hTNFR2 on DCs, monocyte, B cells, and neutrophils in spleen of hTNFR2(BALB/c) humanized mice.
Leukocytes were collected from spleen of wild-type balb/c mice (female, 12 weeks) and homozygous hTNFR2(BALB/c) mice (male, 18 weeks), and analyzed by flow cytometry with anti-mTNFR2 and anti-hTNFR2. hTNFR2 were exclusively detectable in hTNFR2 humanized mice but not in wild-type mice.
Fig.3 Expression analysis of hTNFR2 on monocyte, B cells, and neutrophils in blood of hTNFR2(BALB/c) humanized mice.
Leukocytes were collected from blood of wild-type balb/c mice (female, 12 weeks) and homozygous hTNFR2(BALB/c) mice (male, 18 weeks), and analyzed by flow cytometry with anti-mTNFR2 and anti-hTNFR2. hTNFR2 were exclusively detectable in hTNFR2 humanized mice but not in wild-type mice.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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