hIL15RA
모델명
C57BL/6JSmo-Il15ratm1(hIL15RA)Smoc
카탈로그
NM-HU-215070
모델 상태
Repository Live
유전자 요약
Gene Symbol
Il15ra
모델 설명
검증 데이터
Fig.1 Detection of IL15RA expression in mammary gland and spleen by RT-PCR. Mouse Il15ra mRNA (120 bp) was detectable only in wild-type C57BL/6 mice. Human IL15RA mRNA (124 bp) was detectable only in homozygous hIL15RA knockin mice but not in wild-type mice. Mammary gland and spleen RNA was extracted from 6-week-old male wild-type C57BL/6 (WT)(n=2) and homozygous hIL15RA knockin mice (HO) (n=2), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers.
Abbr. M, marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hIL15RA expression on DC cells and Macrophage in BM of WT C57BL/6 mice and HO hIL15RA mice by FACS. hIL15RA was exclusively detectable in hIL15RA humanized mice but not in wild-type mice. hIL15RA was exclusively detectable on DC cells and Macrophage in hIL15RA humanized mice. Leukocytes were collected from wild-type C57BL/6 mice (male, 6 weeks old) and homozygous HO hIL15RA humanized mice (male, 6 weeks old),stimulated with LPS in vitro(1ug/ml), and analyzed by flow cytometry with anti-mIL15RA , anti-hIL15RA.
Abbr. HO, homozygous; WT, wild type.
당신은 또한 좋아할 수 있습니다
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
조회Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
조회