hIL1RL1
모델명
C57BL/6JSmo-Il1rl1tm4(hIL1RL1)Smoc
카탈로그
NM-HU-2000067
모델 상태
Repository Live
유전자 요약
Gene Symbol
Il1rl1
모델 설명
검증 데이터
Fig1. Detection of IL1RL1 expression in large intestine by RT-PCR in hIL1RL1 mice.
Wild type: only one band at 296 bp with primers F1/R1(mIl1rl1);
Homoygous: only one band at 367 bp with primers F2/R2(hIL1RL1);
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig.2 Exprssion analysis of of hIL1RL1 on Treg cells in spleen in male hIL1RL1/hTSLP (NM-XA-241614) mice, which were generated by crossing hTSLP(NM-HU-2000064) with hIL1RL1(NM-HU-2000067).
Leukocytes were collected from the spleens of 9-week-old wild-type C57BL/6 mice (WT) and hIL1RL1/hTSLP mice, and analyzed by flow cytometry with anti-hIL1RL1 antibody and anti-mIL1RL1 antibody. hIL1RL1 was exclusively detectable on Treg in hIL1RL1/hTSLP mice, whereas mIL1RL1 was exclusively detectable on Treg in wild-type C57BL/6 mice.
Fig.3 Expression of hIL1RL1 on FcεRIα+ cells in Bone marrow in male hIL1RL1/hTSLP (NM-XA-241614) mice, which were generated by crossing hTSLP(NM-HU-2000064) with hIL1RL1(NM-HU-2000067).
Leukocytes were collected from the bone marrow of 9-week-old wild-type C57BL/6 mice (WT) and hIL1RL1/hTSLP mice, and analyzed by flow cytometry with anti-hIL1RL1 antibody and anti-mIL1RL1 antibody. hIL1RL1 was exclusively detectable on FcεRIα+ cells in hIL1RL1/hTSLP mice, whereas mIL1RL1 was exclusively detectable on FcεRIα+ cells in wild-type C57BL/6 mice.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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