Mrgpra3-2A-GFPCre
모델명
C57BL/6JSmo-Mrgpra3em1(2A-GFPCre)Smoc
카탈로그
NM-KI-234359
모델 상태
Sperm cryopreservation
유전자 요약
Gene Symbol
Mrgpra3
모델 설명
검증 데이터
Fig.1 Detection of Mrgpra3-2A-GFPCre expression in DRG, TG, brain, Spinal cord, heart, liver, spleen, lung, kidney, skin, muscle, stomach and intestine by RT-PCR.
Mrgpra3-2A-GFPCre+ (13#): one band at 2070 bp with primers F1/R1(Mrgpra3-2A-GFPCre) in DRG and TG.
Abbr. DRG, dorsal root ganglion; TG, trigeminal ganglia; M, DNA marker; WT, wild type.
Fig1. Cre mediated recombination in dorsal root ganglion of Mrgpra3GFP-Cre/+;Rosa26tdTomato/+ mouse.
Fig2. Detection of EGFP(green) and tdTomato(red) in various tissues of of Mrgpra3GFP-Cre/+;Rosa26tdTomato/+ mouse. The tissues of double-positive mice were cryosectioned and directly examined, revealing expression in the following organs: dorsal root ganglion;A few cells expressed in large intestine, small intestine, thymus, adrenal gland, testicular interstitium;Uninduced group scattered cell expression:Brain, spinal cord, retina, heart, lungs, liver, stomach,salivary glands, brown fat, pituitary gland, kidney, spleen, pancreas, skin.
EGFP is not expressed in the thymus, while its expression pattern in other locations is similar to that of tdTomato. (53-days old, male) (For more detailed information please contact our technical advisor.)
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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