Vav1-2A-Cre

모델명

C57BL/6Smoc-Vav1em1(2A-Cre)Smoc

카탈로그

NM-KI-233228

모델 상태

Sperm cryopreservation

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유전자 요약

Gene Symbol
Vav1

Synonyms

Vav; vav-T

Chromosome

17

NCBI ID

22324

MGI ID

98923

Ensembl ID

ENSMUSG00000034116

Pubmed

Vav1

Human Ortholog

VAV1

모델 설명

The 2A-Cre expression cassette was knocked into the Vav1 gene stop codon site.

검증 데이터

图片1.png

Fig1. Cre mediated recombination in spleen of Vav1Cre/+; Rosa26tdTomato/+ mouse. 

图片2.png

Fig2. Detection of tdTomato(red) in various tissues of Vav1Cre/+; Rosa26tdTomato/+ mouse. The tissues of double-positive mice were cryosectioned and directly examined, revealing expression in the following organs: spleen, thymus, lungs, liver, stomach, brown fat, adrenal glands, kidneys, pancreas, small intestine, colon, testicular interstitium, epididymis, muscles and skin. A few cells expressed in brain, retina, heart, salivary glands, spinal cord, pituitary gland. (25-days old, male) (For more detailed information please contact our technical advisor.) !!!!!!!!

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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