Csf1r-IRES-Cre

모델명

C57BL/6JSmo-Csf1rem3(IRES-iCre)Smoc

카탈로그

NM-KI-190026

모델 상태

Repository Live

PDF 받기

유전자 요약

Gene Symbol
CSF1R

모델 설명

A IRES-iCre expression cassette was knocked into the Csf1r gene stop codon site.
신청분야:Cre recombinase tool

검증 데이터

csf1r.png

Fig1. Flow assay of fluorescent gene expression in peripheral blood macrophages of Csf1r-Cre+/-;R26-mTmG+/- mice. In cre-expressing F4/80 macrophages, tdTomato was excised and the cells were labelled with EGFP; in F4/80 macrophages without cre expression, the cells were labelled with tdtomato and EGFP was not expressed.

image.png

Fig2. Cre mediated recombination in skin of Csf1r Cre/+;Rosa26 tdTomato/+ mice.

image.png

Fig3. Detection of tdTomato(red) in various tissues of Csf1r Cre/+;Rosa26 tdTomato/+ mice. The tissues that express tdTomato include: brain, eyeball, heart, lungs, liver, salivary glands, kidneys, small intestine, large intestine, ovaries, skin, adrenal gland, gallbladder. A small amount of expressiontdTomato are spinal cord. (7.5-weeks old, female) (For more detailed information please contact our technical advisor.) 


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

조회