R26-CAG-Cas9
모델명
C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
카탈로그
NM-KI-00120
모델 상태
Repository Live
유전자 요약
Gene Symbol
Gt(ROSA)26Sor
모델 설명
검증 데이터
Fig1. Analysis of Cas9 expression profile by Western Blot. The CAG-Cas9 KI mice express Cas9 in heart, liver, spleen, lung, kidney, stomach, cortex, cerebellum, testis and muscle.
J***: Cas9 KI mice from other peers
CAG-Cas9: R26-CAG-Cas9 mice (NM-KI-00120) obtained by R26-CAG-LNL-Cas9(NM-KI-00038) crossed with Ella-Cre
Cas9-krab: R26-CAG-3XKRAB-dCas9-IRES-EGFP（NM-KI-18007）
Fig2. Detection of CAS9 expression in R26-CAG-CAS9 mice by WB.
Abbr. M, marker; WT, wild type; HO, homozygous; WAT, white adipose tissue; BAT, brown adipose tissue.
Note. 60 μg of total protein were loaded for BAT and skeletal muscle, and 20 μg for other tissues.
Fig.3 Detection of CAS9 expression in T cells in R26-CAG-CAS9 mice by WB.
Abbr. M, marker; WT, wild type; HO, homozygous.
당신은 또한 좋아할 수 있습니다
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
조회Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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