Tnf-KO

모델명

C57BL/6JSmo-Tnfem1Smoc

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NM-KO-00100

모델 상태

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유전자 요약

Gene Symbol
Tnf

모델 설명

Exon2-3 of Tnf gene were targeted to generate the Tnf knockout mice.
신청분야:Immune and cancer research

검증 데이터

image.png

Fig.1 Detection of TNF expression in spleen and thymus by RT-PCR. 

Wild type: only one band at 209 bp with primers F1/R1(mTnf). 

Abbr. M, DNA marker;  HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of mTnf expression in spleen and thymus by Q-PCR. 

image.png

Fig.3 Detection of mTNF-a expression in serum by ELISA (male, 8wks, n=2). 

Abbr. HO, Homozygous; WT, wild type.

Note.TNF-KO and C57BL/6 mice were i.p. injected with LPS.


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