Foxp3-IRES-DTR-2A-tdTomato(BALB/c)
모델명
BALB/cJSmo-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
카탈로그
NM-KI-200213
모델 상태
Embryo cryopreservation
유전자 요약
Gene Symbol
Foxp3
모델 설명
검증 데이터
CT 26 tumor cells were injected into FOXP3-DTR mice administered with different treatment, and Balb/c mice, respectively. And tumor growth curves of each group were recorded.
Fig 1. The growth of CT26 tumors in Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice. (In collaboration with CrownBio)
Proportion of different type-specific T cells and macrophages in peripheral blood of each group analyzed using FACS
Fig 2. The percentage of different type-specific T cells and macrophages in peripheral blood of CT26 tumor-bearing Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice is detected by FACS. (In collaboration with CrownBio)
Proportion of different type-specific T cells and macrophages in spleen and tumor of each group analyzed using FACS
Fig 3. The percentage of different type-specific T cells and macrophages in spleen and tumor of of CT26 tumor-bearing Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice is detected by FACS. (In collaboration with CrownBio)
Fig 4. DTR mediated cell knockout in spleen of Foxp3-DTR/tdTomato mice (BALB/c).
Fig 5. DTR mediated cell knockout in mesenteric lymph nodes of Foxp3-DTR/tdTomato mice(BALB/c).
당신은 또한 좋아할 수 있습니다
Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
조회Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
조회