hIL21/hIL21R
모델명
C57BL/6JSmo-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
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NM-HU-220038
모델 상태
Repository Live
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Fig 1. Detection of IL21 expression in splenocyte by RT-PCR.
Wild type: only one band at 272 bp with primers F1/R1 (mIl21);
Homozygous: only one band at 304 bp with primers F2/R2 (hIL21);
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig 2. Detection of hIL21 expression in culture supernatants of splenocyte by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Note. Splenocytes from C57BL/6 and homozygous hIL21/hIL21R dKI mice were stimulated with anti-mCD3 antibody in vitro.
Fig 3. Detection of IL21R expression on spleen-derived activated T cells and B cells in hIL21/hIL21R dKI mice.
Note. Splenocytes from C57BL/6 and homozygous hIL21/hIL21R dKI mice were stimulated with anti-mCD3 antibody in vitro.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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