hIL11/hIL11RA
모델명
C57BL/6JSmo-Il11tm1(hIL11)Il11ra1tm1(hIL11RA)Smoc
카탈로그
NM-HU-210372
모델 상태
Repository Live
모델 설명
검증 데이터
Fig.1 Detection of IL11 expression in testis,stomach and lung by RT-PCR in hIL11/hIL11RA dKI mice.
Wild type: only one band at 171 bp with primers F1/R1(mIl11);
Homozygous: only one band at 162 bp with primers F2/R2(hIL11).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of IL11RA expression in testis, stomach and lung by RT-PCR in hIL11/hIL11RA dKI mice.
Wild type: only one band at 289 bp with primers F1/R1(mIl11ra);
Homozygous: only one band at 247 bp with primers F2/R2(hIL11RA).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.3 Detection of hIL11 expression in lung homogenate by ELISA in hIL11/hIL11RA dKI mice.
Abbr. HO, homozygous; WT, wild type.
Note. hIL11/hIL11RA and C57BL/6 mice were injected with LPS.
Fig.4 Detection of human IL11RA expression in hIL11/hIL11RA dKI mice by WB.
Abbr. HO, homozygous; WT, wild type.
Note. The IL11RA Antibody cross-reacted with mouse and humanized IL11RA.
Fig.5 Detection of hIL11RA expression in Kidney in C57BL/6 and HO/HO hIL11/hIL11RA knockin mice by IHC.
Abbr. HO/HO, homozygous; WT, wild type.
Note. The IL11RA Antibody cross-reacted with mouse and humanized IL11RA.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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