F8-KO
모델명
B6.129S-F8tm1Smoc
카탈로그
NM-KO-00012
모델 상태
Repository Live
유전자 요약
Official Symbol
F8
모델 설명
Disease Connection
검증 데이터
Fig 1. Schematic diagram for the F8 gene knockout mice generation strategy
Fig2. Analysis of activated partial thromboplastin time (APTT) in the F8 knock-out mice. The coagulation time in F8-KO mice (NM-KO-00012) was significantly longer than wild-type, and there was no obvious difference in coagulation time between F8-KO (NM-KO-00012) and F8-KO(2) (NM-KO-200608).
F8 gene knockout mice are an ideal animal model for studying the pathogenesis and drug screening of hemophilia A at the whole animal level. In addition, F8 gene knockout mice can provide an ideal animal model and a novel research tool for the screening and evaluation of hemophilia A drugs as well as the gene therapy of hemophilia A. F8 gene knockout mice provide an effective tool for further elucidating the pathogenesis of hemophilia A, for the evaluation and screening of drugs used for the prevention and treatment of hemophilia A, and for the development of new therapies.
당신은 또한 좋아할 수 있습니다
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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