Tsc1-Flox

모델명

C57BL/6Smoc-Tsc1tm1(flox)Smoc

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NM-CKO-200231

모델 상태

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유전자 요약

Official Symbol
Tsc1

모델 설명

These mice carry loxP sites flanking exon 17-18 of Tsc1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tsc1 gene.
신청분야:Research on mTOR signal transduction and respiratory electron transport, ATP synthesis produced by chemical permeation coupling, and heat produced by protein uncoupling

Disease Connection

Tuberous Sclerosis
Autism Spectrum Disorder
Tuberous Sclerosis
Anterior Segment Dysgenesis
Tuberous Sclerosis

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

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