Il33-KO(2)

모델명

C57BL/6Smoc-Il33em2Smoc

카탈로그

NM-KO-190436

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Il33

Synonyms

Il-33; Il1f11; NF-HEV; 9230117N10Rik

NCBI ID

77125

MGI ID

1924375

Ensembl ID

ENSMUSG00000024810

Pubmed

Il33

Human Ortholog

IL33

모델 설명

Il33-KO(2) mice(Stock No.NM-KO-190436) carry a knockout allele derived from the targeted deletion of exon 3-7. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(3) mice(Stock No.NM-KO-210206) carrying the exon 2 deletion.
신청분야：immune

Disease Connection

Alzheimer's disease

Phenotype(s)

MGI:5790841

Reference(s)

Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;

검증 데이터

1.png

Fig1. IL33 were not detected in the Il33 knockout mice by western blot.

간행물

Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling
References：Frontiers in Immunology

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