CAG-hACE2-IRES-Luc-Tg
모델명
C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
카탈로그
NM-TG-200002
모델 상태
Repository Live
유전자 요약
Official Symbol
모델 설명
검증 데이터
Figure 1. Luciferase expression of the CAG-hACE2-IRES-Luciferase transgenic mice.
Figure 2. Western blot analysis of ACE2 protein from the CAG-hACE2-IRES-Luciferase transgenic mice.
Figure 3. Virus titers in the lungs of hACE2 Tg mice after SARS-CoV-2 infection. Groups of hACE2 Tg mice and wild type mice were inoculated with the same dose of SARS-CoV-2, the result shows that hACE2 Tg mice were highly susceptible to SARS-CoV-2 infection.
Figure 4. Body weight change in hACE2 Tg mice after drug treatment.
Figure 5. The viral load in the lung tissues of hACE2 Tg mice after drug treatment.
간행물
당신은 또한 좋아할 수 있습니다
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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