hALB/hFCRN(2)
모델명
C57BL/6JSmo-Albtm3(hALB)Fcgrttm2(hFCGRT)Smoc
카탈로그
NM-HU-200278
모델 상태
Repository Live
모델 설명
검증 데이터

Fig.1 Detection of hALB (A) and mALB (B) expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Fig.2 Expression characterization of hFCRN in hALB/hFCRN dKI mice by Western blot. (Arrow indicates expected molecular weight and asterisk indicates a nonspecific band)

Fig.3 In vivo PK profiles of TAA scfv-anti HSA VHH in hALB/hFCRN mice (female, 10-12weeks, n=3 mice/timepoint).
(In cooperation with the third party).

Fig.4 Blood concentration curves of test articles in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party)

Table 1 Noncompartmental Analysis (NAC) results of test articles in hFcRn/hALB dKI mice. (In cooperation with the third party)

Fig.5 Fitting curves of blood concentration in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party)
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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