hAppNL-G-F

모델명

C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc

카탈로그

NM-HU-2000088

모델 상태

Repository Live

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유전자 요약

Official Symbol
App

모델 설명

The endogenous mouse App gene was replaced by human AppNL-G-F.
신청분야:Alzheimer's disease research

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Fig1. Detection of APP expression in brain by RT-PCR.

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Fig2. (A) β-Amyloid (6E10) staining of WT and hAPPNL-G-F mice at 1, 3 and 6 months (magnification, 40x and 100x). (B) Statistics of 6E10 positive plaque area.

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Fig3. (A) Thioflavine S staining of WT and hAPPNL-G-F mice at 1, 3 and 6 months (magnification, 40x and 100x). (B) Statistics of ThiS positive plaque area.


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