hCD40(BALB/c)

모델명

BALB/cAnSmoc-Cd40em1(hCD40)/Smoc

카탈로그

NM-HU-2000047

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
CD40

모델 설명

The endogenous mouse Cd40 gene was replaced by human CD40 gene.
신청분야:Immunotherapy,drug screening

검증 데이터

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Fig1. Analysis of hCD40 expression in PBMC in the hCD40 mice by FACS. hCD40 was expressed on B cells in PB.

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Fig2. Analysis of hCD40 expression on splenic B cells by FACS. hCD40 was expressed on the B cells in the spleen.

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Fig3. Analysis of human CD40 expression on splenic DCs and macrophages by FACS . The homozygous KI mouse expresses human CD40 on DCs and macrophages.(Provided by CrownBio)



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