hCLDN6

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C57BL/6Smoc-Cldn6em1(hCLDN6)Smoc

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NM-HU-225034

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Cldn6

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The endogenous mouse Cldn6 gene was replaced by human CLDN6 gene.


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image.png

Fig.1 Detection of CLDN6 expression in lung by RT-PCR. 

Wild type: only one band at 304 bp with primers F1/R1(mCldn6);

Homozygous: only one band at 141 bp with primers F2/R2(hCLDN6).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human CLDN6 expression in hCLDN6 knockin Mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

Note. The anti-human CLDN6 Antibody cross-reacted with mouse CLDN6 and humanized CLDN6. 


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