hF12

모델명

C57BL/6Smoc-F12tm1(hF12)/Smoc

카탈로그

NM-HU-210017

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
F12

모델 설명

The endogenous mice F12 gene was replaced by human F12 gene.
신청분야:drug screening

검증 데이터

image.png

Fig1. Detection of F12 expression in liver by RT-PCR. 

Wild type: only one band at 318 bp with primers F1/R1(mF12);

Homozygous: only one band at 274 bp with primers F2/R2(hF12); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human F12 (A) and mouse F12 (B) expression in serum by ELISA (male, 8-11wks, n=2). 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig.3 Detection of hF12 expression in serum by ELISA (male, n=3). 

Abbr. HO, homozygous; WT, wild type.  


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회