hTIGIT(BALB/c,2)

모델명

BALB/cAnSmoc-Tigittm4(hTIGIT)Smoc

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NM-HU-200245

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Tigit

모델 설명

The endogenous mice Tigit gene was replaced by human TIGIT gene.While hTIGIT(BALB/c) (Stock No.NM-HU-2000043) have been pulled from shelves for some reasons.


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Fig.1 Detection of TIGIT expression in large intestine by RT-PCR. 

Wild type: only one band at 126 bp with primers F1/R1(mTigit);

Homozygous: only one band at 168 bp with primers F2/R2(hTIGIT).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig.2 Detection of hTIGIT expression on splenocytes-derived activated T cells in hTIGIT KI mice.

Note. Splenocytes from BALB/c and HO hTIGIT mice were stimulated with ConA in vitro. 


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