hCD3E

모델명

C57BL/6Smoc-Cd3eem1(hCD3E) Smoc

카탈로그

NM-HU-00114

모델 상태

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유전자 요약

Official Symbol
CD3E

Synonyms

CD3; T3e; AI504783; CD3epsilon

NCBI ID

12501

MGI ID

88332

Ensembl ID

ENSMUSG00000032093

Pubmed

CD3E

Human Ortholog

CD3E

모델 설명

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.
신청분야：Immunotherapy,cancer research,drug screening

검증 데이터

CD3E-1.png

Fig1. The expression of human CD3E in the peripheral blood cells derived from heterozygous or homozygous humanized mice was confirmed by FACS. 

CD3E-2.png

Fig2. Detection of T cell subsets in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

CD3E-3.png

Fig3. Detection of B and NK cells in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

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Fig4. In vitro T cell activation with heterozygous or homozygous CD3E humanized mice.

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Fig5. Cytokine analysis of anti-human CD3E antibody treated hCD3E mice. 

The data is provided by Crownbio.

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