hIL1RL1

모델명

C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc

카탈로그

NM-HU-2000067

모델 상태

Sperm cryopreservation

PDF 받기

유전자 요약

Official Symbol
Il1rl1

모델 설명

The endogenous mouse Il1rl1 gene was replaced by human IL1RL1 gene.

신청분야:Cytokine humanization model;drug screening

검증 데이터

image.png

Fig1. Detection of IL1RL1 expression in large intestine by RT-PCR in hIL1RL1 mice

Wild type: only one band at 296 bp with primers F1/R1(mIl1rl1);

Homoygous: only one band at 367 bp with primers F2/R2(hIL1RL1); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Expression of hIL1RL1 on CD4+ T cells in spleen in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).

image.png

Fig3. Expression of hIL1RL1 on mast cells in bone marrow in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회