hCCR5

모델명

C57BL/6Smoc-Ccr5tm1(hCCR5)/Smoc

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NM-HU-2000065

모델 상태

Embryo cryopreservation

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유전자 요약

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Ccr5

모델 설명

The endogenous mouse Ccr5 gene was replaced by human CCR5 gene.
신청분야:Immunotherapy,drug screening

검증 데이터

NM-HU-2000065 hCCR5.png

Fig1. Analysis of CCR5 gene expression in the spleen by RT-PCR.

Mouse Ccr5 mRNA was detectable by P1/2(869bp), human CCR5 mRNA was detectable by P1/3(607bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human CCR5 and mouse Ccr5 in the spleen.



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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

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