hIL10

모델명

C57BL/6Smoc-Il10tm4(hIL10)/Smoc

카탈로그

NM-HU-2000063

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Il10

모델 설명

The endogenous mouse Il10 gene was replaced by human IL10 gene.
신청분야:Cytokine humanization model;drug screening

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image.png

Fig1. Detection of IL10 expression in bladder by RT-PCR. 

Wild type: only one band at 362 bp with primers F1/R1(mIl10);

Homozygous: only one band at 196 bp with primers F2/R2(hIL10).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of human and mouse IL10 expression in serum by ELISA (n=2). 

Abbr. HO, homozygous; WT, wild type.

Note. hIL10 and C57BL/6 mice were i.p. injected with LPS for 2h.




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