hHER3(2)

모델명

C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc

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NM-HU-225068

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Erbb3

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The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.


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image.png

Fig.1 Detection of ERBB3 expression in colon by RT-PCR. 

Wild type: only one band at 343 bp with primers F1/R1(mErbb3);

Homozygous: only one band at 305 bp with primers F2/R2(hERBB3).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human hHER3 expression in hHER3(2) knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, homozygous; PC, positive control, MC38-hHER3 cells.

Note. The anti-human hHER3 antibody cross-reacted with mouse hHER3 and humanized hHER3. 


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