hIL11/hIL11RA

모델명

C57BL/6Smoc-Il11em1(hIL11)Il11ra1tm1(hIL11RA)/Smoc

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NM-HU-210372

모델 상태

Embryo cryopreservation

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유전자 요약

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Tnfrsf4

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Il11ra1

모델 설명

hIL11(NM-HU-204981) was crossed with hIL11RA (NM-HU-204982) to generate hIL11/hIL11RA mice.
신청분야:inmmue therapy;drug screening

검증 데이터

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Fig1. Detection of hIL11 expression in lung homogenate by ELISA. Abbr. HO, homozygous; WT, wild type. Note. hIL11/hIL11RA and C57BL/6 mice were injected with LPS.

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Fig2. Detection of hIL11RA expression in Kidney in C57BL/6 and HO/HO hIL11/hIL11RA knockin mice by IHC. Abbr. HO/HO, homozygous; WT, wild type. Note. The anti-human IL11RA Antibody cross-reacted with mouse IL11RA and humanized IL11RA.


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