hTLR2

모델명

C57BL/6Smoc-Tlr2em2(hTLR2)Smoc

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NM-HU-190066

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Tlr2

모델 설명

The endogenous mouse Tlr2 gene was replaced by human TLR2 gene.
신청분야:Immunotherapy,cancer research,drug screening

검증 데이터

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Fig1. Strain specific hTLR2 expression analysis in homozygous hTLR2 mice by flow cytometry. Macrophages of PBMC were collected from WT and homozygous hTLR2 mice, and analyzed by flow cytometry with species-specific anti-hTLR2 and anti-mTLR2 antibody.  hTLR2 was detectable in a subset of macrophages in homozygous hTLR2 mice, and the mTLR2 was not expressed.


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