Grp-Cre

모델명

C57BL/6Smoc-Grpem1(Cre-WPRE-pA)Smoc

카탈로그

NM-KI-200305

모델 상태

Sperm cryopreservation

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유전자 요약

Official Symbol
Grp

모델 설명

Cre-WPRE-pA expression cassette was knocked into the Grp gene start codon site.

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Fig1. Cre mediated recombination in brain of GrpCre/+;Rosa26tdTomato/+ mouse. (7-weeks old, male)

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Fig2. Cre mediated recombination in spinal cord of GrpCre/+;Rosa26tdTomato/+ mouse. (10-weeks old, female) 

Abbr: DH: Dorsal Horn

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Fig3. Detection of tdTomato(red) in various tissues of GrpCre/+;Rosa26tdTomato/+ mouse. Expression tissues include: brain, salivary gland, kidney, skin, pituitary. A few cells expressed in  retina, lung, spinal cord, pancreatic islets, colon, small intestine, spleen, testis and epididymis, muscle, thymus. Tissues that unexpressed include myocardium, liver, stomach, brown fat, adrenal gland, DRG.(7-weeks old, male) (For more detailed information please contact our technical advisor.) 


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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