Pbsn-2A-CreERT2

모델명

C57BL/6Smoc-Pbsnem1(V5-2A-CreERT2-WPRE-polyA)Smoc

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NM-KI-200190

모델 상태

Sperm cryopreservation

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유전자 요약

Official Symbol
Pbsn

모델 설명

A V5-2A-CreERT2-WPRE-polyA expression cassette was knocked into the Pbsn gene stop codon site.
신청분야:Cre recombinase tool,epithelial cells of the prostate.

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Fig1. Expression Pattern of Tomato in PbsnCreERT2/+;Rosa26tdTomato/+ mice.

CreERT2-mediated recombination in prostate epithelial cells of PbsnCreERT2/+ ; Rosa26tdTomato/+ mice. This strain represents an effective tool for generating prostate specific-targeted mutants.

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Fig2. Cre mediated recombination in prostate of PbsnCreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig3. Detection of tdTomato(red) in various tissues of PbsnCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: prostate, salivary gland. A few cells expressed in adrenal gland, pancreas, testis, muscle and thymus. Tissues that unexpressed include brain, spinal cord, eyeball, heart, lung, liver, stomach, brown fat, kidney, colon, small intestine, spleen, and skin. (9-week old, male) (For more detailed information please contact our technical advisor.)


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