Krt5-IRES-CreERT2

모델명

C57BL/6Smoc-Krt5em1(IRES-CreERT2)Smoc

카탈로그

NM-KI-200168

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
Krt5

모델 설명

A IRES-CreERT2 expression cassette was knocked into the Krt5 gene stop codon site.
신청분야:Cre recombinase tool

검증 데이터

Krt5-IRES-CreERT2-1 - 副本.png

Fig. 1 Detection of tdTomato (red) in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+  mouse. CreERT2-mediated recombination in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+ mouse. Some leakiness were detected in the epidermis and hair follicle prior to tamoxifen exposure.

Krt5-IRES-CreERT2-2 - 副本.png

Fig. 2 Detection of tdTomato (red) in various tissues of Krt5CreERT2/+; Rosa26tdTomato/+ mice. 

CreERT2-mediated recombination in the brown fat and submandibular gland can be induced by tamoxifen. Some leakiness were detected in the skin,eyes and testis prior to tamoxifen exposure.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회